A Coup d'oeil Of The Average Blood Glucose and SGPT Levels of Drug Induced Diabetic Experimental Rats Treated with the Cissampelos Pareira L. (Menispermaceae) Root Extract

Abstract

We discuss a three dimensional model to predict the SGPT levels of the drug induced diabetic rats belonging to the group G4T (group 4 Test) category in the experiments of Ankit Kumar et al. (see, Ankit Kumar, Ravindra Semwal, Ashutosh Chauhan, Ruchi Badoni Semwal, Subhash Chandra, Debabrata Sircar, Partha Roy and Deepak Kumar Semwal, Evaluation of antidiabetic effect of Cissampelos pareira L. (Menispermaceae) root extract in streptozotocin-nicotinamide-induced diabetic rats via targeting SGLT2 inhibition, Phytomedicine Plus 2 (2022) 100374, 11pp., https://doi.org/10.1016/j.phyplu.2022.100374 ). As per the experimental procedure of Ankit Kumar et al. (op. cit.), the rats of the group G4T were orally administered the Cissampelos pareira root extract at the rate of 500mg/kg/day for twenty eight days after the induction of diabetes in them using streptozotocin and nicotinamide. Treating the SGPT levels of the rats of the group G4T as a function of the number of days of the experimental study and their weekly measured average blood glucose levels, our model explains about 95.71% of the variance in the values of the SGPT of these rats based on the residual sum of squares approach. From the applications point of view, we also present our detailed analysis of the correlation matrix of the dataset under examination